ACE-031 (ACVRB2) is a synthetic active receptor type 2B which is mainly found in the muscle. It is designed for proteins such as myostatin, GDF11 and activin A and B. The main focus, however, is on the myostatin. When myostatin binds to an activin receptor type IIB in the muscle, the growth of the muscle fibers is inhibited. Myostatin is mainly responsible for the muscle reduction and the setting of the limits for the muscle build-up. By the peptide ACE-031 this is strongly, up to completely restricted.
The synthetic ACE-031 filters in principle the muscle-building inhibiting proteins and deactivates them quasi.
It reduces the so-called leptin concentration responsible for the fat build-up and increases the fat-degrading effect of the so-called adiponectin.